Sprite _newSprite = Sprite.Create(Texture, Rect);

public List<Sprite> _spriteList;//Сюда пихаешь спрайты через инспектор
Dictionary<string, Sprite> _spriteDictionary = new Dictionary<string, Sprite>();

void Start()
{
foreach(var item in _spriteList)
{
if(!_spriteDictionary.ContainsKey(item.name))
{
_spriteDictionary.Add(item.name, item);
}
}

public Sprite GetSprite(string _name)//тут вытягиваешь по имени спрайта
{
return (_spriteDictionary.ContainsKey(_name))? _spriteDictionary[_name]: null;
}

Shader "Custom/MainShader" {
    Properties {
  _MainTex ("Albedo (RGB)", 2D) = "white" {}
  _MainTex2 ("Mask (RGB)", 2D) = "white" {}
  _Value ("Value", Range(0,1)) = 0.0
    }
    SubShader {
  Tags
  {
   "Queue"="Transparent"
   "IgnoreProjector"="True"
   "RenderType"="Transparent"
   "PreviewType"="Plane"
   "CanUseSpriteAtlas"="True"
  }

  CGPROGRAM

  #pragma surface surf Standard fullforwardshadows

  sampler2D _MainTex;
  sampler2D _MainTex2;
  half _Value;

  struct Input
  {
   float2 uv_MainTex;
   float2 uv_MainTex2;
  };

  void surf (Input IN, inout SurfaceOutputStandard o)
  {
   fixed4 c = tex2D (_MainTex, IN.uv_MainTex);
   fixed4 m = tex2D (_MainTex2, IN.uv_MainTex2);

   o.Albedo = lerp(c,m,_Value);
   o.Alpha = c.a;
  }

  ENDCG
    }
    FallBack "Diffuse"

o.Alpha = c.a;

o.Alpha = m.a;

Shader "Unlit/ssss"
{
    Properties
    {
  [PerRendererData] _MainTex ("Texture", 2D) = "white" {}
  _MainTex2("Texture2", 2D) = "white" {}
  _Value("Value", Range(0,1)) = 0.0
    }
    SubShader
    {
  Tags {
  "Queue" = "Transparent"
  "IgnoreProjector" = "True"
  "RenderType" = "Transparent"
  "PreviewType" = "Plane"
  "CanUseSpriteAtlas" = "True"
    }
   Cull Off
   Lighting Off
   ZWrite Off
   Fog{ Mode Off }
   Blend One OneMinusSrcAlpha

  Pass
  {
   CGPROGRAM
   #pragma vertex vert
   #pragma fragment frag

   
   #include "UnityCG.cginc"

   struct appdata
   {
    float4 vertex : POSITION;
    float2 uv : TEXCOORD0;
   };

   struct v2f
   {
    float2 uv : TEXCOORD0;
    float4 vertex : SV_POSITION;
   };

   sampler2D _MainTex;
   float4 _MainTex_ST;
   sampler2D _MainTex2;
   float4 _MainTex2_ST;
   float _Value;

   v2f vert (appdata v)
   {
    v2f OUT;
    OUT.vertex = UnityObjectToClipPos(v.vertex);
    OUT.uv = v.uv;
    return OUT;
   }
   
   fixed4 frag (v2f i) : SV_Target
   {
    fixed4 col = tex2D(_MainTex, i.uv);
    fixed4 col2 = tex2D(_MainTex2, i.uv);
    col2.rgb *= col2.a;
    fixed3 colr = lerp(col.rgb, col2.rgb, _Value);
    col.rgb = colr.rgb * col.a;
    return col;
   }
   ENDCG
  }
    }
}